Common brand names: Mycelex, Lotrimin


Description: Clotrimazole is an antifungal drug best known for treating vaginal yeast infections in women.


Dental uses: Clotrimazole is available as a troche (lozenge) for treating fungal infections in the mouth. It is considered by some to be the drug of choice for the treatment of candidal fungal infections (thrush) in the mouths of some patients with AIDS. It is pleasant tasting and far more palatable than nystatin.


Dosages for dental purposes: The typical dose is to dissolve one 10-milligram clotrimazole troche in the mouth five times per day for 14 days. A 1-percent clotrimazole ointment can be applied directly to the involved oral tissues four times per day for denture stomatitis.


Concerns and possible side effects: Clotrimazole can cause occasional burning and irritation on application, and occasional nausea.

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